The First One-Pot Synthesis of l-7-Iodotryptophan from 7-Iodoindole and Serine, and an Improved Synthesis of Other l-7-Halotryptophans DRM Smith, T Willemse, DS Gkotsi, W Schepens, BUW Maes,S Ballet , RJM Goss, Org. Lett., 2014, 16, 2622–2625. A simple and scalable one-pot biotransformation enables direct access to l-halotryptophans, including l-7-iodotryptophan, from the corresponding haloindoles. The biotransformation utilizes an easy to prepare bacterial cell lysate that may be stored as the lyophilizate for several months and utilized as a catalyst as and when required. Copyright © 2014 American Chemical Society Keyword: Hyperbaric Chamber…
Continue reading